Xenogears for PSone. It might be popular NOW (I can't find a damn copy ANYWHERE, and I'm not paying $50 on eBay for it) but back when I first had it, it seemed like NO one else liked it in Houston OR in New Orleans. Hmm.
Arcade games? The Simpsons, for one (I only say that because it was HARD to find around here) and the King Of Fighters series. Mmmm, Mai Shiranui
The little Freddy Krueger guy was pretty cool too.
As far as Zombies Ate My Neighbors, there WAS a sequel to it (and it DID have Zeke and Julie in it)
It's called Ghoul Patrol.
And why the hell can I not find the ROM for the original Splatterhouse?!?