Deus Ex again.
It's sorta less poopy when you play through with maxed-out Rifle skills, but a heavily modded assault shotgun can one-shot pretty much anything from the other side of the map. Hilarious, but game breaking!
Now I'm playing through with the crossbow and melee weapons while trying to be ultra-sneaky. You have to run away a lot since tranquilizer darts take forever to actually knock someone out.
