I like a number of his things. Eraserhead's mad decent. Blue Velvet is great. Wild at Heart is pretty good. And I really liked Dumbland. (
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But I tried to write a paper on Inland Empire, a movie I could barely sit through. I was dying watching it. Same thing with Mulholland Drive, albeit to a lesser extent. He keeps trying to wrap dream logic around life while whenever you try explaining a dream you had, you sound like a fucking asshole.
Also, I do like his paintings a bit, so there's always that. And to his credit, he's the only one that's ever made a movie that scares me, so he gets turbo props for that.