Resident Evil 4

[Dr. Boogie]

You can do both routes. You just have to go back and change the gate switch.

For the El Gigante route, I just bought an RPG because I was low on ammo. Some people say you can drop the two huge boulders on him, but I've never been able to do that. Instead, I just dropped one in front of him, and while he was preoccupied with destroying it, I shot him with the shotgun until he fell over, and then blasted the parasite with the RPG.

For the chainsaw sisters, if you use select to skip the cutscene, you'll actually gain a second or two while one of them busts through the wall. Just run up the ladder and run back towards the ladder that first got you onto those walkways. Then, you just blast the two of them with the shotgun once they get together, and nail them in the head with the rifle a few times while they lie on the ground. Repeat as necessary.