I just used some tanks like the Thing and the Hulk (got the Gold edition for the 360) and made the other two interchangeable for spice. Thor and Wolverine got a lot of play there.
Me and three friends went through this game a while back. Here's who we used:
Iron Man (me)
Human Torch
Iceman
Deadpool
The guy who played as Human Torch decided to switch to Mr. Fantastic halfway through the game and proceeded to get every single bonus in the whole fucking game. If you're having a hard time, play with him as he is broken.
Hybrid Mode
